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Age Later: Health Span, Life Span, and the New Science of Longevity

Age Later: Health Span, Life Span, and the New Science of Longevity

by Nir Barzilai M.D.


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Available for Pre-Order. This item will be available on June 16, 2020


How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties?

Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s.

One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline.

In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

Product Details

ISBN-13: 9781250230850
Publisher: St. Martin''s Publishing Group
Publication date: 06/16/2020
Pages: 288
Sales rank: 399,528
Product dimensions: 9.10(w) x 6.30(h) x 1.10(d)

About the Author

NIR BARZILAI, M.D., is the founding Director of the Institute for Aging Research at Albert Einstein College of Medicine and the Nathan Shock Center for Excellence in the Basic Biology of Aging and the Einstein Glenn Center for the Biology of Human Aging. Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others. Co-founder of CohBar, a clinical stage biotechnology company focused on increasing health span by developing treatments for age-related diseases. Age Later is his first publication for consumers.

Table of Contents


1. One Hundred Years Young

The Mysteries of Aging

What Makes SuperAgers Stay Healthy?

Studying Centenarians

Designing a Study Without a Control Group

Meeting Our First AJ Centenarians and Their Offspring

A Perfect Genome?

Centenarians’ Interactions with Their Environments

Do as I Say, Not as I Do

2. Why We Age

Recent Theories

The Search for Protection from Aging

Eating Less May Lead to More Healthy Years

Unlocking the Secrets in Fat

Caloric Restriction: A Mixed Bag of Effects

Aging Begins Before We’re Born

SuperAgers’ Top Secrets

3. Cholesterol: Is More Better?

Unlocking Cholesterol’s Longevity Secrets

Are there Really Good Gene Mutations?

Solving the Mystery of Helpful Gene Mutations

The Benefits of CETP Personified

A Mutation That Adds Years to Life Span?

4. Growth Hormone: Less Is More

Less Growth May Lead to an Exceptionally Long Life

Growth Hormone Clues from Our Centenarians

Epigenetic Mechanisms Can Increase Longevity

Making the Most of Our Findings

Growth Hormones Don’t “Grow” Life Span

5. Unraveling the Longevity Mystery Deep Inside Our Cells

A Match Made on Earth

Mitochondria’s Hidden Purpose

Resilient to the End

A CohBar Is Born

Searching for Promising Peptides

6. The Quest to Prove Aging Can Be Targeted

Choosing an Existing Drug to Prove Our Point

Getting the FDA on Board

How the TAME Study Works

Who’s Going to Pay for All This?

Metformin Is the Tool, Not the Goal

7. Making Eighty the New Sixty

The Price of Progress

Collaboration Is the Key to Speed

Long, Healthy Life Span Versus Immortality

The Gap Between Making Drugs and Making Drugs Available

8. Stop the Clock

How Old Is Old?

Use It or Lose It

Antioxidants and Hormesis

Thriving in the Shadow of Stress

Preventing the Loss of Muscle Mass as We Age

Exercise Plus Metformin

Feeding Our Longevity

Hydrating Wisely

Prevent Obesity

Nutraceuticals Are in the Works

The Magic Pills We’ve Been Wishing For

When We Eat Matters

Our DNA Has Something to Say

Stay Mentally Sharp

Other Promising Practices

How to Decide What’s Good for You

9. Bright Horizons

The Unparalleled Power of Omics

Personalized Medicine

Advances in Early Detection

Pioneering Explorations

Reversing Cellular Age

Genetic Engineering



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