| Johnny Depp | Mad Hatter |
| Anne Hathaway | The White Queen |
| Mia Wasikowska | Alice Kingsleigh |
| Helena Bonham Carter | The Red Queen |
| Rhys Ifans | Zanik Hightopp |
| Matt Lucas | Tweedledee/Tweedledum |
| Ed Speleers | James Harcourt |
| Sacha Baron Cohen | Time |
| Stephen Fry | Cheshire Cat |
| Matt Vogel | Wilkins |
| Alan Rickman | Blue Caterpillar |
| Michael Sheen | White Rabbit |
| Timothy Spall | Bayard |
| Paul Whitehouse | March Hare |
| Barbara Windsor | Dormouse |
| Lindsay Duncan | Helen Kingsleigh |
| Leo Bill | Lord Hamish Ascot |
| Geraldine James | Lady Ascot |
| Andrew Scott | Dr. Addison Bennet |
| Richard Armitage | King Oleron |
| Paul Hunter | Chess King |
| Wally Wingert | Humpty Dumpty |
| Meera Syal | Nobody |
| Hattie Morahan | Queen Elsewhere |
| Louis Serkis | Young Hatter |
| Joanna Bobin | Alexandra |
| Amelia Crouch | Young Mirana |
| Leilah de Meza | Young Iracebeth |
| Simone Kirby | Tyva Hightopp |
| Joe Hurst | Bim Hightopp |
| Siobhan Redmond | Bumalig Hightopp |
| Oliver Hawkes | Young Bim Hightopp |
| Frederick Warder | Poomally Hightopp |
| Eve Hedderwick Turner | Paloo Hightopp |
| Tom Godwin | Pimlick Hightopp |
| Daniel Hoffmann-Gill | Boatswain |
| Jamie Baughan | First Mate |
| Matt Wilman | Helmsman |
| Siobhan McSweeney | Witzender |
| Owain Rhys Davies | Delivery Frog |
| Edward Petherbridge | Gentleman Fish |
| Richard Syms | Board Member |
| Neil Edmond | Footman |
| Bill Thomas | Driver |
Technical Credits
| James Bobin | Director |
| Alex Smith | Set Decoration/Design |
| Valeria Andino | Producer |
| Colleen Atwood | Costumes/Costume Designer |
| Eric Bates | Animator |
| Paul Becker | Executive Producer |
| John Berger | Set Decoration/Design |
| Lucy Bevan | Casting |
| Tim Burton | Producer |
| Peter Cavaciuti | Camera Operator |
| Karen Clarke | Production Manager |
| Evan Clover | Animator |
| Shaun Cobley | Camera Operator |
| Neil Corbould | Special Effects Supervisor |
| Chad Cortvriendt | Producer |
| Stuart Dryburgh | Cinematographer |
| Danny Elfman | Score Composer |
| Jann K. Engel | Set Decoration/Design |
| Teri Fairhurst | Set Decoration/Design |
| Sarah Finlay | Set Decoration/Design |
| David Gimenez | Animator |
| Mark Goddard | Asst. Director |
| Richard Goodwin | Asst. Director |
| Nick Gottschalk | Art Director |
| Rodrigo Gutierrez | Camera Operator |
| Richard Hardy | Set Decoration/Design |
| Patrick Harris | Set Decoration/Design |
| Dan Hennah | Production Designer |
| Justin Henton | Animator |
| Scott Herbertson | Set Decoration/Design |
| Sony Pictures Imageworks | Animator |
| Francesca Jaynes | Choreography |
| Jeremy Johns | Co-producer |
| Peter King | Makeup |
| Ren Klyce | Sound/Sound Designer |
| Benjamin Kousholt | Animator |
| Jeff Markwith | Set Decoration/Design |
| Nando Martinez | Animator |
| Stephen Mascarenhas | Executive Producer |
| Richard Mays | Set Decoration/Design |
| Ian McFadyen | Set Decoration/Design |
| Sophie Neil | Set Decoration/Design |
| Al Nelson | Sound/Sound Designer |
| Francois-Xavier Nhieu | Animator |
| Stephen Painter | Animator |
| Mary Pike | Set Decoration/Design |
| Shaun Roth | Special Effects |
| Joe Roth | Producer |
| John G. Scotti | Executive Producer |
| Richard Selway | Art Director |
| Jennifer Todd | Producer |
| Suzanne Todd | Producer |
| Vince Truitner | Animator |
| Aoife Warren | Set Decoration/Design |
| Andrew Weisblum | Editor |
| Lotta Wolgers | Set Decoration/Design |
| Robert Woodruff | Set Decoration/Design |
| Linda Woolverton | Screenwriter |
