The "greatest gamble" in the life of Philip Eden (Richard Dix) is to restore his long-estranged daughter Alice's (Dorothy Wilson) will to live. Escaping from prison after serving 15 years for unintentional homicide, Eden discovers that Alice has been raised as a weak, vacillating neurotic by her vengeful mother Florence (Erin O'Brien-Moore). He promptly "kidnaps" the girl and builds up her health and spirit, finally turning her over to her sweetheart Stephen (Bruce Cabot) before voluntarily giving himself up to the Law. His Greatest Gamble allows Richard Dix to combine both his established screen personae: The misunderstood hero and the virile man of action. Not surprisingly, Dix's legions of fans ate it up like candy.