| Tom Holland | Peter Parker / Spider-Man |
| Samuel L. Jackson | Nick Fury |
| Zendaya | Michelle Jones |
| Cobie Smulders | Maria Hill |
| Jon Favreau | Happy Hogan |
| J.B. Smoove | Actor |
| Jacob Batalon | Ned |
| Martin Starr | Mr. Harrington |
| Tony Revolori | Flash Thompson |
| Marisa Tomei | May Parker |
| Jake Gyllenhaal | Quentin Beck / Mysterio |
| Angourie Rice | Betty |
| Numan Acar | Dimitri |
| Remy Hii | Brad Davis |
| Michael Mando | Mac Gargan |
| Hemky Madera | Mr. Delmar |
| Toni Garrn | The Seamstress |
| Helene Cardona | Austrian Backpacker |
| Sitara Attaie | Dutch lady |
| Zach Barack | Actor |
| Michael Iacono | Airport Kid Traveler |
| Meagan Holder | Pretty Tourist |
| Anthony Molinari | Mob Guy |
| Ria Fend | Tourist in Venice |
| Davina Sitaram | London Tourist |
| Sonia Goswami | Tourist |
| Massi Furlan | Flight attendant |
| Jeroen Van Koningsbrugge | Dutch Hooligan 1 |
| Ruth Horrocks | Tourist |
| Jo Wheatley | Armed Security Officer |
| Joseph Long | Mob Boss |
| Joakim Skarli | London Tourist |
| Emily Tebbutt | Venice Tourist-Boat Scene |
| Hiten Patel | British Station Staff |
| Jessica VanOss | Student |
| Camille Kinloch | Midtown High School Student |
| Peter Arpesella | Airplane Pilot |
| Hannah Kurczeski | Student |
| Giada Benedetti | Italian Custom Officer |
| Peter Bankolé | Mob Boss |
| Samantha Mishinski | Student |
| Tuwaine Barrett | Police Officer |
| Zoha Rahman | Classmate |
| Lukás Bech | Farmer |
| Michael Roos | Dutch Hooligan 2 |
| Shafali Rani Chung | London Tourist |
| Rich Lawton | Journalist |
| Raymond Rosario | TSA Agent |
| Rocco Wu | Peter's Art Classmate |
| Komal Charania | Student Boom Operator / High School Student |
| Darren Lee Campbell | Victoria's Crew |
| Daniel Olson | Czech Guy |
| Brian Law | Queens Reporter |
| Joe David Walters | Pawn Shop Owner |
| Jaylen Davis | Tourist |
| Patrick Holly | Party Goer |
| Annie Pisapia | Traveler |
| Xiao Xue Xu Lin | Passerby |
| Tiziana Coste | Local Venetian |
| Leonys Delossantos | Guy staring at spiderman |
| Eric Patrick Cameron | Midtown High Student |
| Yasmin Mwanza | Classmate |
| Bruno Bilotta | Mob Boss 2 |
| Brendan Murphy | Police Officer |
| Shari Abdul | High School Reporter |
| Ken Byrd | Post Office Customer |
| Adrian Mozzi | Venice Local |
| Emmanuel Rodriguez | Airport traveler |
| Blair Barnette | Queens Reporter |
| Daphne Cheung | Passport Clerk |
| Kristen Alminta | Police Officer |
| Jimena Larraguivel | Mexican Villager |
| Géraldine Lamarre | Traffic Warden |
| Maria Alexandrova | Tourist in Venice |
| Angela Koo Reina | Mob Boss (as Angela Koo) |
| Gavin Lee Lewis | Londoner |
| Alessandro Sciarra | Screaming Kid |
| Vincent Angel | Midtown High Student |
| Peter Dawson | Tourist in Venice |
| Peter Dawson | Tourist in Venice |
| Antonín Masek | Bellboy |
| Tony Mardon | Londoner |
| Daniel Rennis | Cab Driver |
| Vincent Frattini | Venice Local |
| Tyler Luke Cunningham | Student |
| Clay Pel-is | London Tourist |
| Luigi Boccanfuso | Italian builder in Venice |
| Andrew Dunkelberger | Courier |
| Susanne Schraps | Berlinerin |
| Bradley Wj Miller | Passerby |
| Dian Cathal | American Reporter |
| Lucas Antoine Starrets | Tourist |
| Daham Kandanarrachchi | London Passerby |
| Anna Benamati | Shop Owner in Venice |
| Sokol Cahani | Mob Boss |
| Tyrone Love | Venice Wedding Guest |
| Ferroz Fernandez | Tourist in Venice |
| Luigi Petrazzuolo | Gondolier |
| Serkan Safak | Film Maker |
| Daniel Ryves | Dad Collecting Kids |
| Avondre E.D. Beverley | High school student (uncredited) |
| Paolo Braghetto | Poliziotto |
| Dante Brattelli | High School Student |
| Graham Burton | London Passerby |
| Gaylene Butler | Dinner Guest |
| Jake Cerny | Airport Traveler (uncredited) |
| Sam Chuck | High School Student |
| Al Clark | Cowboy Plane Passenger |
| Victoria Coburn | Passerby |
| Sean Coleman | Yearbook Student |
| Kristianne-Kaith Domingo | Passerby (uncredited) |
| Charlie Rhea Esquér | Mexican Survivor |
| Parker Everlith | Tourist |
| Cynthia Garbutt | Charity Dinner Guest (uncredited) |
| Thomas Goodridge | Tourist in Venice |
| Jake Hanson | Rooftop Dad (uncredited) |
| Nicholle Hembra | Saved Londoner |
| Lindy Hennessey | Prague Hotel Guest |
| Michael Hennessy | Hotel Guest |
| Roman Ibragimov | Bar Customer |
| Timothy Christian Jansen | High School Student |
| Gian Kalch | . Venetian Fish Stall Owner (uncredited) |
| Keon Kendrick | Flight Attendant |
| Kath Leroy | Czech Traditional Dancer (uncredited) |
| Faith Logan | High School Student (uncredited) |
| Buddhi Madushan | Tourist |
| Aristou Meehan | Italian Boy |
| James Melville | London Worker |
| Melissa B. Miller | Tourist |
| Julia Mollin | Flute Player (uncredited) |
| Amanda Musso | Carnival Hot Girl (uncredited) |
| Emily Ng | Italian Tourist (uncredited) |
| Vincent Paolicelli | Basketball Player (uncredited) |
| Karen Parks | Charity Event Attendee (uncredited) |
| Aleksandrs Petukhovs | London Passerby |
| Martin Polak | Czech Reveler |
| Jivan Xander Ramesh | Pedestrian |
| Sofia Renee | High School Student (as Sofia Carmona) |
| Cailan Robinson | Victoria's Crew |
| Monae Samone | Midtown High Student |
| Karen-J Sear | . American Tourist (uncredited) |
| Ilya Tank Shilov | Venice Touris |
| Paul Slim | Tourist (uncredited) |
| Michal Snajdr | Czech Tourist |
| Theo | Tourist |
| Patrick Turner | London Crowd Member |
| Oskar Ulvestad | Street Pedestrian |
| Lesdy Vanessa | Tourist |
| Dale Wilder | German Office Worker |
| Jan Zalabak | Tourist in Town |
Technical Credits
