| Shirley MacLaine | Harriet Lauler |
| Amanda Seyfried | Anne Sherman |
| Thomas Sadoski | Robin Sands |
| Anne Heche | Elizabeth |
| Philip Baker Hall | Edward |
| Ann'Jewel Lee | Brenda |
| Gedde Watanabe | Gardener |
| Tom Everett Scott | Ronald Odom |
| Joel Murray | Joel Mueller |
| Yvette Freeman | Housekeeper |
| Valerie Ross | Wanda Byers |
| Steven Culp | Sam Sherman |
| Adina Porter | Bree Wilson |
| Todd Louiso | Dr. Morgan |
| Chloe Wepper | Agency Receptionist |
| Sarah Baker | Hair Dresser |
| Nikki McCauley | Dawn DJ |
| Marshall Bell | Mr. Daniels |
| Jesse Burch | Moderator |
| Marcy Jarreau | Focus Group Woman 1 |
| Brooke Trantor | Focus Group Woman 2 |
| Joshua Harto | Focus Group Man 1 |
| Basil Hoffman | Nervous Older Man |
| Natalija Nogulich | Middle Aged Woman |
| Alanna Ubach | Gynecologist |
| Bill Glass | Father Piper |
| Millicent Martin | Margaret Dumont |
| John Billingsley | Father Reilly |
Technical Credits
| Mark Pellington | Director,Producer |
| Douglas Cumming | Art Director |
| Kirk D'Amico | Producer |
| Nathan Matthew David | Score Composer |
| Mary Jo Devenney | Sound Mixer |
| Stuart Ross Fink | Screenwriter |
| Kevin Forester | Executive Producer |
| Phillip B. Goldfine | Executive Producer |
| Alix Hester | Costumes/Costume Designer |
| Richard Hoover | Production Designer |
| Andrew Karpen | Executive Producer |
| Eric Koretz | Cinematographer |
| Heidi Levitt | Casting |
| Edward Licht | Asst. Director |
| Liza Richardson | Musical Direction/Supervision |
| Anne-Marie Mackay | Producer |
| Shirley MacLaine | Executive Producer |
| Aaron Magnani | Executive Producer |
| Danny Roth | Executive Producer |
| Teddy Schwarzman | Executive Producer |
| Amanda Seyfried | Executive Producer |
| Tony Smiley | Sound Mixer |
| Daniel Steinman | Executive Producer |
| Damiano Tucci | Executive Producer |
| Theresa Won | Co-producer |
| Julia Wong | Editor |
