Multiple Sclerosis: Advances in Clinical Trial Design, Treatment and Future Perspectives

Multiple Sclerosis: Advances in Clinical Trial Design, Treatment and Future Perspectives

Paperback(Softcover reprint of the original 1st ed. 1996)

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Overview

This book reviews the therapeutic developments in clinical trial design that have resulted in new treatment options for patients suffering from MS. Important ethical considerations that arise with the new treatments are included, as well as the perspective on the emergence of MS as a treatable disease.

Product Details

ISBN-13: 9781852330330
Publisher: Springer London
Publication date: 07/17/1998
Edition description: Softcover reprint of the original 1st ed. 1996
Pages: 364
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

1 Recent Advances and Future Challenges in Multiple Sclerosis Clinical Trial Design.- 2 Pathogenesis of Multiple Sclerosis: Relationship to Therapeutic Strategies.- 3 Future of Multiple Sclerosis Therapeutics: Rational Approaches Targeting Putative Pathogenic Mechanisms.- 4 Statistical and Design Considerations for Multiple Sclerosis Clinical Trials.- 5 Clinical Outcome Measures for Multiple Sclerosis.- 6 Use of Neuropsychologic Outcome Measures in Multiple Sclerosis Clinical Trials: Current Status and Strategies for Improving Multiple Sclerosis Clinical Trial Design.- 7 “Quality of Life” Assessment in Multiple Sclerosis Clinical Trials: Current Status and Strategies for Improving Multiple Sclerosis Clinical Trial Design.- 8. Magnetic Resonance Imaging: Current Status and Strategies for Improving Multiple Sclerosis Clinical Trial Design.- 9. Magnetic Resonance Imaging of Patients with Isolated Idiopathic Optic Neuritis, Brainstem Syndromes and Myelopathy.- 10 Strategies to Delay the Onset of Clinically Definite Multiple Sclerosis in Patients with Monosymptomatic Presentations of Optic Neuritis, Brainstem Syndromes or Myelopathy.- 11 Treatment of Multiple Sclerosis with Type I Interferons.- 12 Treatment of Multiple Sclerosis with Methotrexate.- 13 Treatment of Multiple Sclerosis with Copolymer 1.- 14 Treatment of Multiple Sclerosis with Cladribine.- 15 Ethical Considerations Raised by Clinical Trials.- 16 The Emergence of Multiple Sclerosis as a “Treatable” Condition: An Historical Perspective.

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