Thompson & Thompson Genetics in Medicine / Edition 8

by Robert L. Nussbaum MD, FACP, FACMG, Roderick R. McInnes CM, MD, PhD, FRS(C), FCAHS, FCCMG, Huntington F Willard

Overview

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders.

• Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics.
• Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. 
• Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos.

• Immerse yourself in updated graphics, full-color text, illustrations, line diagrams, and clinical photos of genetic diseases.
• Explore the latest genetic content available in order to remain up to date on the most current trends in the field.
• Take advantage of a double-page clinical case study section that demonstrates and reinforces general principles of disease inheritance, pathogenesis, diagnosis, management, and counseling.
• Enhance your critical thinking skills and better retain information. Each chapter ends with up to 5 quick genetic "problems" related to what has just been reviewed, with answers provided in the back of the book.
• Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. You'll also access USMLE-style and multiple choice questions.

Product Details

ISBN-13:	9781437706963
Publisher:	Elsevier Health Sciences
Publication date:	06/04/2015
Pages:	560
Sales rank:	247,831
Product dimensions:	8.50(w) x 10.70(h) x 0.80(d)

About the Author

Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.

Table of Contents

Chapter 1 Introduction

Chapter 2 Introduction to the Human Genome

Chapter 3 The Human Genome: Gene Structure and Function

Chapter 4 Human Genetic Diversity: Mutation and Polymorphism

Chapter 5 Principles of Clinical Cytogenetics and Genome Analysis

Chapter 6 The Chromosomal and Genomic Basis of Disease: Disorders of the Autosomes and Sex Chromosomes

Chapter 7 Patterns of Single-Gene Inheritance

Chapter 8 Complex Inheritance of Common Multifactorial Disorders

Chapter 9 Genetic Variation in Populations

Chapter 10 Identifying the Genetic Basis for Human Disease

Chapter 11 The Molecular Basis of Genetic Disease

Chapter 12 The Molecular, Biochemical, and Cellular Basis of Genetic Disease

Chapter 13 The Treatment of Genetic Disease

Chapter 14 Developmental Genetics and Birth Defects

Chapter 15 Cancer Genetics and Genomics

Chapter 16 Risk Assessment and Genetic Counseling

Chapter 17 Prenatal Diagnosis and Screening

Chapter 18 Application of Genomics to Medicine and Personalized Health Care

Chapter 19 Ethical and Social Issues in Genetics and Genomics

Cases

Editorial Reviews

Reviewer: Luis F Escobar, MD., MS. (Peyton Manning Children's Hospital)
Description: This update of an established general textbook of medical genetics comes 50 years after the original by James and Margaret Thompson and eight years after the previous edition. This eighth edition is masterfully written by Nussbaum, McInnes, and Willard. Widely known as Thompson and Thompson, this is an instrumental book in the field. This edition comes with access to an ebook version of great utility.
Purpose: While meeting the goal of providing students with a framework for understanding the field of medical genetics and genomics on which they can build their continuing education, the book also provides a link between basic science and clinical application of genetic knowledge.
Audience: The audience for this wonderful book is broad, ranging from undergraduate students in science to graduate students in medical genetics. Medical genetics residents may find it a unique resource for understanding the clinical applicability of the genetic science. It is also a useful tool for students and physicians preparing to take the American Board of Medical Genetics and Genomics certification exams. Seasoned clinicians may find it helpful as a consulting tool for reviewing basic concepts in medical genetics.
Features: Among the unique details that distinguish this from other books in the field are the brief review questions at the end of each chapter. They represent key points that readers must understand and help reinforce what they've learned. In addition, the design of the book has become reader friendly with exquisite illustrations and well-planned artistic features. There are two helpful indexes, one by chapter and a subject keyword index at the end of the book.
Assessment: The ebook version is easy to access. I was able to sign into the site without difficulty and review the content with easy-to-use navigation tools. I did not test the display in different formats, but an average resolution monitor provides a good display of figures and text.

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