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Winter's Basic Clinical Pharmacokinetics / Edition 6

Winter's Basic Clinical Pharmacokinetics / Edition 6

by Paul Beringer PharmDPaul Beringer PharmD
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Winter’s Basic Clinical Pharmacokinetics helps readers apply pharmacokinetics and therapeutic drug monitoring to patient care.
An easy-to-read, case-study format has made this text a favorite among students and clinicians. Divided into two parts, Part I reviews basic pharmacokinetic principles, and Part II illustrates the clinical application of these principles to common problems.
  • Extensive explanations emphasize major concepts and accompany complex equations.
  • Figures help visualize concepts
  • NEW chapters include drug dosing in renal disease, pediatric considerations, and pharmacogenomics, as well as antifungals and expansion of the cytotoxic and immunosuppressant therapies
  • Includes cases that address pediatric considerations and pharmacogenomics
  • Updates include new information on the clinical use of serum drug concentrations
  • New Learning Objectives at the beginning of each chapter highlight the key concepts

Product Details

ISBN-13: 9781496346421
Publisher: LWW
Publication date: 11/09/2017
Edition description: Sixth
Pages: 624
Product dimensions: 6.00(w) x 9.00(h) x 0.90(d)

Table of Contents

Contributors vii

Preface ix

Part I Basic Principles

1 Pharmacokinetic Processes and Parameters 3

2 Selecting the Appropriate Equation and Interpretation of Measured Drug Concentrations 57

3 Drug Dosing in Kidney Disease and Dialysis 98

4 Pediatrics 129

5 Pharmacogenetics 154

Part II Drug Monographs

6 Aminoglycoside Antibiotics 163

7 Antifungal Agents: Triazoles 213

8 Carbamazepine 241

9 Cytotoxic Anticancer Drugs: Methotrexate and Busulfan 256

10 Digoxin 281

11 Immunosuppressants: Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolic Acid 320

12 Lithium 358

13 Phenobarbital 371

14 Phenytoin 398

15 Valproic Acid 446

16 Vancomycin 467


Appendix 1 Nomograms for Calculating Body Surface Area 497

Appendix 2 Common Equations Used Throughout the Text 499

Appendix 3 Algorithm for Evaluating and Interpreting Plasma Concentrations 505

Appendix 4 Glossary of Terms and Abbreviations 510

Index 515

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